|
The Boveri–Sutton chromosome theory (also known as the chromosome theory of inheritance or the Sutton–Boveri theory) is a fundamental unifying theory of genetics which identifies chromosomes as the carriers of genetic material.〔(1902: Theodor Boveri (1862-1915) and Walter Sutton (1877-1916) propose that chromosomes bear hereditary factors in accordance with Mendelian laws ) Genetics and Genomics Timeline. Genome News Network an online publication of the J. Craig Venter Institute.〕〔(Chromosome theory of inheritance ) Holmgren Lab Northwestern University.〕〔Mader, S. S. (2007). Biology 9th Ed. McGraw Hill Higher Education, Boston, MA, USA. ISBN 978-0-07-325839-3〕 It correctly explains the mechanism underlying the laws of Mendelian inheritance by identifying chromosomes with the paired factors (particles) required by Mendel's laws. It also states that chromosomes are linear structures with genes located at specific sites called loci along them.〔 It states simply that chromosomes, which are seen in all dividing cells and pass from one generation to the next, are the basis for all genetic inheritance. ==Background== The chromosome theory of inheritance is credited to papers by Walter Sutton in 1902〔Sutton, W.S. (1902). (On the morphology of the chromosome group in ''Brachystola magna.'' ) Biol. Bull. 4: 24-39.〕 and 1903,〔Sutton, W.S. (1903). (The chromosomes in heredity. ) Biol. Bull. 4: 231-251. Partial reproduction in: Classic Papers in Genetics (1959) (Peters, J.A., ed.). Prentice-Hall, Englewood Cliffs, pp. 27-41.〕 as well as to independent work by Theodor Boveri during roughly the same period.〔Boveri, T.H. (1904). Ergebnisse über die Konstitution der chromatischen Substanz des Zelkerns. Fisher, Jena.〕 Boveri was studying sea urchins, in which he found that all the chromosomes had to be present for proper embryonic development to take place. Sutton's work with grasshoppers showed that chromosomes occur in matched pairs of maternal and paternal chromosomes which separate during meiosis and "may constitute the physical basis of the Mendelian law of heredity".〔Sutton, W.S. (1902), p. 39.〕 This groundbreaking work led E.B. Wilson in his classic text to name the chromosome theory of inheritance the "Sutton-Boveri Theory".〔Wilson, E.B. (1925). ''The Cell in Development and Heredity'', 3rd edition. Macmillan, New York. p. 923.〕 Wilson was close to both men, since the young Sutton was his student and the prominent Boveri was his friend (in fact, Wilson dedicated the afore-mentioned book to Boveri). Although the naming precedence is now often reversed to "Boveri-Sutton", there are some who argue that Boveri didn't actually articulate the theory until 1904.〔Martins, L.A.-C.P. (1999). (Did Sutton and Boveri propose the so-called Sutton-Boveri chromosome hypothesis? ) Genet. Mol. Biol. (). Vol.22, n.2, pp. 261-272 (2011-03-03 ).〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Boveri–Sutton chromosome theory」の詳細全文を読む スポンサード リンク
|